Dataset Card for Adverse Drug Reaction Data v2

Dataset Summary

ADE-Corpus-V2 Dataset: Adverse Drug Reaction Data. This is a dataset for Classification if a sentence is ADE-related (True) or not (False) and Relation Extraction between Adverse Drug Event and Drug. DRUG-AE.rel provides relations between drugs and adverse effects. DRUG-DOSE.rel provides relations between drugs and dosages. ADE-NEG.txt provides all sentences in the ADE corpus that DO NOT contain any drug-related adverse effects.

Supported Tasks and Leaderboards

Sentiment classification, Relation Extraction

Languages

English

Dataset Structure

Data Instances

Config - Ade_corpus_v2_classification

{
      'label': 1, 
      'text': 'Intravenous azithromycin-induced ototoxicity.'
}

Config - Ade_corpus_v2_drug_ade_relation

{ 
    'drug': 'azithromycin', 
    'effect': 'ototoxicity', 
    'indexes': {
                  'drug': {
                            'end_char': [24], 
                            'start_char': [12]
                          }, 
                  'effect': {
                            'end_char': [44], 
                            'start_char': [33]
                            }
                }, 
    'text': 'Intravenous azithromycin-induced ototoxicity.'
    
}

Config - Ade_corpus_v2_drug_dosage_relation

{
    'dosage': '4 times per day', 
    'drug': 'insulin', 
    'indexes': {
                'dosage': {
                            'end_char': [56], 
                            'start_char': [41]
                        }, 
                'drug': {
                          'end_char': [40], 
                          'start_char': [33]}
                        }, 
    'text': 'She continued to receive regular insulin 4 times per day over the following 3 years with only occasional hives.'
}

Data Fields

Config - Ade_corpus_v2_classification

• text - Input text.
• label - Whether the adverse drug effect(ADE) related (1) or not (0).

Config - Ade_corpus_v2_drug_ade_relation

• text - Input text.
• drug - Name of drug.
• effect - Effect caused by the drug.
• indexes.drug.start_char - Start index of drug string in text.
• indexes.drug.end_char - End index of drug string in text.
• indexes.effect.start_char - Start index of effect string in text.
• indexes.effect.end_char - End index of effect string in text.

Config - Ade_corpus_v2_drug_dosage_relation

• text - Input text.
• drug - Name of drug.
• dosage - Dosage of the drug.
• indexes.drug.start_char - Start index of drug string in text.
• indexes.drug.end_char - End index of drug string in text.
• indexes.dosage.start_char - Start index of dosage string in text.
• indexes.dosage.end_char - End index of dosage string in text.

Data Splits

Train
23516

Dataset Creation

Curation Rationale

[Needs More Information]

Source Data

Initial Data Collection and Normalization

[Needs More Information]

Who are the source language producers?

[Needs More Information]

Annotations

Annotation process

[Needs More Information]

Who are the annotators?

[Needs More Information]

Personal and Sensitive Information

[Needs More Information]

Considerations for Using the Data

Social Impact of Dataset

[Needs More Information]

Discussion of Biases

[Needs More Information]

Other Known Limitations

[Needs More Information]

Additional Information

Dataset Curators

[Needs More Information]

Licensing Information

[Needs More Information]

Citation Information

@article{GURULINGAPPA2012885,
title = "Development of a benchmark corpus to support the automatic extraction of drug-related adverse effects from medical case reports",
journal = "Journal of Biomedical Informatics",
volume = "45",
number = "5",
pages = "885 - 892",
year = "2012",
note = "Text Mining and Natural Language Processing in Pharmacogenomics",
issn = "1532-0464",
doi = "https://doi.org/10.1016/j.jbi.2012.04.008",
url = "http://www.sciencedirect.com/science/article/pii/S1532046412000615",
author = "Harsha Gurulingappa and Abdul Mateen Rajput and Angus Roberts and Juliane Fluck and Martin Hofmann-Apitius and Luca Toldo",
keywords = "Adverse drug effect, Benchmark corpus, Annotation, Harmonization, Sentence classification",
abstract = "A significant amount of information about drug-related safety issues such as adverse effects are published in medical case reports that can only be explored by human readers due to their unstructured nature. The work presented here aims at generating a systematically annotated corpus that can support the development and validation of methods for the automatic extraction of drug-related adverse effects from medical case reports. The documents are systematically double annotated in various rounds to ensure consistent annotations. The annotated documents are finally harmonized to generate representative consensus annotations. In order to demonstrate an example use case scenario, the corpus was employed to train and validate models for the classification of informative against the non-informative sentences. A Maximum Entropy classifier trained with simple features and evaluated by 10-fold cross-validation resulted in the F1 score of 0.70 indicating a potential useful application of the corpus."
}

Contributions

Thanks to @Nilanshrajput , @lhoestq for adding this dataset.